The domain within your query sequence starts at position 71 and ends at position 355; the E-value for the Exo5 domain shown below is 1.3e-82.

SPMERFHLKYLYVTDLCTQNWCELQMVYGKELPGSLTPEKAAVLDTGASIHLAKELELHD
LVTVPIATKEDAWAVKFLNILAMIPALQSEGRVREFPVFGEVEGIFLVGVIDELHYTSKG
ELELAELKTRRRPVLPLPAQKKKDYFQVSLYKYIFDAMVQGKVTPASLIHHTKLCLDKPL
GPSVLRHARQGGVSVKSLGDLMELVFLSLTLSDLPAIDTLKLEYIHQETATILGTEIVAF
EEKEVKSKVQHYVAYWMGHRDPQGVDVEEAWKCRTCDYVDICEWR

Exo5

Exo5
PFAM accession number:PF09810
Interpro abstract (IPR019190):

In Saccharomyces cerevisiae (Baker's yeast), Exo5 is a single strand DNA specific 5'exonuclease, which is involved in mitochondrial DNA replication and recombination. It has the capacity to slide across 5'double-stranded DNA or 5'RNA sequences and resumes cutting two nucleotides downstream of the double-stranded-to-single-stranded junction or RNA-to-DNA junction, respectively [ (PUBMED:20086101) ]. It degrades single-stranded, but not double-stranded, DNA from the 5'-end, and the products are dinucleotides, except the 3'-terminal tri- and tetranucleotides, which are not degraded. The initial hydrolytic cut of exonuclease V on the dephosphorylated substrate produces a mixture of dinucleoside monophosphates and trinucleoside diphosphates [ (PUBMED:3286646) ]. Exo5 is specific for single-stranded DNA and does not hydrolyze RNA [ (PUBMED:20086101) ].

GO function:single-stranded DNA 5'-3' exodeoxyribonuclease activity (GO:0045145)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Exo5