The domain within your query sequence starts at position 447 and ends at position 879; the E-value for the FANCAA domain shown below is 1.4e-196.

ANAGQKIKELLLDIGDVSERVSFLKKAVDQRNKAITSLNEAMNVSCALLSHPEGDRPIAC
TITTSWSRLELRDMLMATCTLENSSSFSLDQGWTLCIQVLTSSSALDLDGTGSAFTYTIP
VDRLGPGSRREVTLPLGPSESGVLDLPVTMSCWLFYSLREVVGAALAPSDPLEAPYLEQF
PLSLPKQEGVCLPLCKRTVDMLQCLRFAGAATHPAQAPCMPGPACEPVETFLKTCQAPGS
EPTGAASLRAKYLPPSTASIRVSAGLLRAALEDSHSGFHLCSATLRWLLAENAAVDVVRA
QTLSSIQGIAPDGTDVNLTVHEVAVTDLSPAGPIQAVEIQVESSSLANMCRAHHAIIRRI
QTMVTEQAALGSSPPDLRMQYLQQIHANHQELLREVQALRDQLCTEDELSSCSTAQKLLH
IYKQLRNPSLVLL

FANCAA

 FANCAA
PFAM accession number:PF15146
Interpro abstract (IPR029251):

Fanconi anemia (FA) is a human disorder characterized by cancer susceptibility and cellular sensitivity to DNA crosslinks and other damages. The FA complex repairs the interstrand cross-linking (ICL) lesions and coordinates activities of the downstream DNA repair pathway including nucleotide excision repair, translesion synthesis, and homologous recombination. It is required for the monoubiquitylation of FANCD2 and FANCI heterodimer. The FA core complex consists of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL, FANCM, FANCT (UBET2), FAAP100 and FAAP24 [ (PUBMED:29017571) (PUBMED:20347428) ].

Fanconi anemia-associated protein of 100kDa (FAAP100) is component of the Fanconi anemia (FA) core complex, which plays a central role in FA-associated DNA damage response. FAAP100 is essential for the stability and function of the complex [ (PUBMED:17396147) ].

GO process:interstrand cross-link repair (GO:0036297)
GO component:Fanconi anaemia nuclear complex (GO:0043240)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry FANCAA