The domain within your query sequence starts at position 157 and ends at position 251; the E-value for the FKBP_C domain shown below is 5e-23.
|PFAM accession number:||PF00254|
|Interpro abstract (IPR001179):|
Synonym(s): Peptidylprolyl cis-trans isomerase
FKBP-type peptidylprolyl isomerases (EC 220.127.116.11) in vertebrates, are receptors for the two immunosuppressants, FK506 and rapamycin. The drugs inhibit T cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. Peptidylprolyl isomerases accelerate protein folding by catalysing the cis-trans isomerisation of proline imidic peptide bonds in oligopeptides. These proteins are found in a variety of organisms.
|GO process:||protein folding (GO:0006457)|