FlgI

• PFAM accession number: PF02119
• Interpro abstract (IPR001782):

  The flgH, flgI and fliF genes of Salmonella typhimurium encode the major proteins for the L, P and M rings of the flagellar basal body [ (PUBMED:2544561) ]. In fact, the basal body consists of four rings (L,P,S and M) surrounding the flagellar rod, which is believed to transmit motor rotation to the filament [ (PUBMED:2129540) ]. The M ring is integral to the inner membrane of the cell, and may be connected to the rod via the S (supramembrane) ring, which lies just distal to it. The L and P rings reside in the outer membrane and periplasmic space, respectively.

  The sequences of the FlgH, FlgI and FliF gene products have been determined [ (PUBMED:2544561) ]. FlgH and FlgI, which are exported across the cell membrane to their destinations in the outer membrane and periplasmic space, have typical N-terminal cleaved signal-peptide sequences [ (PUBMED:2544561) (PUBMED:3549691) ]. FlgH is predicted to have an extensive beta-sheet structure, in keeping with other outer membrane proteins, and FlgI is thought to have even more beta-structure content [ (PUBMED:2544561) ]. Several aspects of the DNA sequence of these genes and their surrounds suggest complex regulation of the flagellar gene system.

• GO process: bacterial-type flagellum-dependent cell motility (GO:0071973)
• GO component: bacterial-type flagellum basal body, distal rod, P ring (GO:0009428), outer membrane-bounded periplasmic space (GO:0030288)
• GO function: structural molecule activity (GO:0005198)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry FlgI