FliE |
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| PFAM accession number: | PF02049 |
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| Interpro abstract (IPR001624): | Four genes from the major Bacillus subtilis chemotaxis locus have been shown to encode proteins that are similar to the Salmonella typhimurium FlgB, FlgC, FlgG and FliF proteins; a further gene product is similar to the Escherichia coli FliE protein [ (PUBMED:1905667) ]. All of these proteins are thought to form part of the hook-basal body complex of the bacterial flagella [ (PUBMED:1905667) ]. The FlgB, FlgC and FlgG proteins are components of the proximal and distal rods; FliF forms the M-ring that anchors the rod assembly to the membrane; but the role of FliE has not yet been determined [ (PUBMED:1905667) ]. The similarity between the proteins in these two organisms suggests that the structures of the M-ring and the rod may be similar [ (PUBMED:1905667) ]. Nevertheless, some differences in size and amino acid composition between some of the homologues suggest the basal body proteins may be organised slightly differently within B. subtilis [ (PUBMED:1905667) ]. From gel electrophoresis and autoradiography of 35S-labelled S. typhimurium hook-basal body complexes and the deduced number of sulphur-containing residues in FliE, the stoichiometry of the protein in the hook-basal body complex has been estimated to be about nine subunits [ (PUBMED:1551848) ]. FliE does not undergo cleavage of a signal peptide, nor does it show any similarity to the axial components like the rod or hook proteins, which are thought to be exported by the flagellum-specific export pathway [ (PUBMED:1551848) ]. On this evidence, it has been suggested that FliE may be in the vicinity of the MS ring, perhaps acting as an adaptor protein between ring and rod substructures [ (PUBMED:1551848) ]. |
| GO process: | bacterial-type flagellum-dependent cell motility (GO:0071973) |
| GO component: | bacterial-type flagellum (GO:0009288) |
| GO function: | structural molecule activity (GO:0005198), motor activity (GO:0003774) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry FliE