SMART: Pfam domain FliS

FliS

PFAM accession number:	PF02561
Interpro abstract (IPR003713):	The fliD operon of several bacteria consists of three flagellar genes, fliD, fliS, and fliT, and is transcribed in this order [ (PUBMED:8550529) ]. In Bacillus subtilis the operon encoding the flagellar proteins FliD, FliS, and FliT is sigma D-dependent [ (PUBMED:8195064) ]. FliS is a flagellin-specific T3S chaperone that binds in 1:1 stoichiometry to the C-terminal region of flagellin and facilitates its export, preventing polymerization in the cytoplasm [ (PUBMED:11327763) (PUBMED:12620624) (PUBMED:16806204) ]. The fliS gene is necessary for flagellation. In Aeromonas, deletion of this gene (called flaJ) resulted in the complete loss of motility, flagellin expression, and adherence [ (PUBMED:11401962) ].
GO process:	bacterial-type flagellum assembly (GO:0044780)

PFAM accession number:

PF02561

Interpro abstract (IPR003713):

The fliD operon of several bacteria consists of three flagellar genes, fliD, fliS, and fliT, and is transcribed in this order [ (PUBMED:8550529) ]. In Bacillus subtilis the operon encoding the flagellar proteins FliD, FliS, and FliT is sigma D-dependent [ (PUBMED:8195064) ].

FliS is a flagellin-specific T3S chaperone that binds in 1:1 stoichiometry to the C-terminal region of flagellin and facilitates its export, preventing polymerization in the cytoplasm [ (PUBMED:11327763) (PUBMED:12620624) (PUBMED:16806204) ]. The fliS gene is necessary for flagellation. In Aeromonas, deletion of this gene (called flaJ) resulted in the complete loss of motility, flagellin expression, and adherence [ (PUBMED:11401962) ].

GO process:

bacterial-type flagellum assembly (GO:0044780)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry FliS