SMART: Pfam domain GIDA

GIDA_assoc

PFAM accession number:	PF13932
Interpro abstract (IPR026904):	The GidA associated domain 3 is a motif that has been identified at the C terminus of protein GidA. It consists of 4 helices, the last three being rather short and forming small bundle at the top end of the first longer one. It is here named helical domain 3 because in GidA it is preceded by two other C-terminal helical domain (based on crystal structures [ (PUBMED:18565343) (PUBMED:19446527) ]). GidA is an tRNA modification enzyme found in bacteria and mitochondria. Based on mutational analysis this domain has been suggested to be implicated in binding of the D-stem of tRNA [ (PUBMED:19446527) ] and to be responsible for the interaction with protein MnmE [ (PUBMED:18565343) ].

PFAM accession number:

PF13932

Interpro abstract (IPR026904):

The GidA associated domain 3 is a motif that has been identified at the C terminus of protein GidA. It consists of 4 helices, the last three being rather short and forming small bundle at the top end of the first longer one. It is here named helical domain 3 because in GidA it is preceded by two other C-terminal helical domain (based on crystal structures [ (PUBMED:18565343) (PUBMED:19446527) ]). GidA is an tRNA modification enzyme found in bacteria and mitochondria. Based on mutational analysis this domain has been suggested to be implicated in binding of the D-stem of tRNA [ (PUBMED:19446527) ] and to be responsible for the interaction with protein MnmE [ (PUBMED:18565343) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry GIDA_assoc