SMART: Pfam domain HBB

HBB

PFAM accession number:	PF06777
Interpro abstract (IPR010643):	HBB is the domain on DEAD-box eukaryotic DNA repair helicases ([intenz:3.6.1.-]) that appears to be a unique fold. It's conformation is of alpha-helices 12-16 plus a short beta-bridge to the FeS-cluster domain at the N-terminal. The full-length XPD protein verifies the presence of damage to DNA and allows DNA repair to proceed. XPD is an assembly of several domains to form a doughnut-shaped molecule that is able to separate two DNA strands and scan the DNA for damage. HBB helps to form the overall DNA-clamping architecture [ (PUBMED:18578568) ]. This family represents a conserved region within a number of eukaryotic DNA repair helicases ([intenz:3.6.1.-]).

PFAM accession number:

PF06777

Interpro abstract (IPR010643):

HBB is the domain on DEAD-box eukaryotic DNA repair helicases ([intenz:3.6.1.-]) that appears to be a unique fold. It's conformation is of alpha-helices 12-16 plus a short beta-bridge to the FeS-cluster domain at the N-terminal. The full-length XPD protein verifies the presence of damage to DNA and allows DNA repair to proceed. XPD is an assembly of several domains to form a doughnut-shaped molecule that is able to separate two DNA strands and scan the DNA for damage. HBB helps to form the overall DNA-clamping architecture [ (PUBMED:18578568) ]. This family represents a conserved region within a number of eukaryotic DNA repair helicases ([intenz:3.6.1.-]).

This is a PFAM domain. For full annotation and more information, please see the PFAM entry HBB