The domain within your query sequence starts at position 13 and ends at position 364; the E-value for the HECT_2 domain shown below is 2.6e-80.

EVRRRLQSALLILGGPDEGGMHLDISITPTSLLVRTPDGCTEIRLPAGVRLVPSSCGGLQ
YISGDGLHLRLRVQAESSPRNSSGCSPCPVRTGALWSESGAAIPTPLLIGLFIREKMTVL
LGTLSS

HECT_2

 HECT_2
PFAM accession number:PF09814
Interpro abstract (IPR019193):

This entry consists of E3 ubiquitin-protein ligases which accept ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfer it to substrates, generally promoting their degradation by the proteasome [ (PUBMED:15749827) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry HECT_2