The domain within your query sequence starts at position 14 and ends at position 150; the E-value for the IFN-gamma domain shown below is 8.2e-57.
LMAVSGCYCHGTVIESLESLNNYFNSSGIDVEEKSLFLDIWRNWQKDGDMKILQSQIISF YLRLFEVLKDNQAISNNISVIESHLITTFFSNSKAKKDAFMSIAKFEVNNPQVQRQAFNE LIRVVHQLLPESSLRKR
IFN-gamma |
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PFAM accession number: | PF00714 |
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Interpro abstract (IPR002069): | Interferon gamma (IFN-gamma) is produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma shows antiviral activity and has important immunoregulatory functions. It is a potent activator of microphages and had antiproliferative effects on transformed cells. It can potentiate the antiviral and antitumor effects of the type I interferons. The crystal structures of a number IFN-gamma proteins have been solved, including bovine interferon-gamma at 2.0-A [ (PUBMED:10666622) ] and human IFN-gamma at 2.9-A [ (PUBMED:10860730) ]. |
GO process: | immune response (GO:0006955) |
GO component: | extracellular region (GO:0005576) |
GO function: | interferon-gamma receptor binding (GO:0005133) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry IFN-gamma