The domain within your query sequence starts at position 1 and ends at position 955; the E-value for the IKI3 domain shown below is < 1e-12.

MRNLKLHRTLEFRDIQAPGKPQCFCLRAEQGTVLIGSERGLTEVDPVRREVKTEISLVAE
GFLPEDGSGCIVGIQDLLDQESVCVATASGDVIVCNLSTQQLECVGSVASGISVMSWSPD
QELLLLATAQQTLIMMTKDFEVIAEEQIHQDDFGEGKFVTVGWGSKQTQFHGSEGRPTAF
PVQLPENALPWDDRRPHITWRGDGQYFAVSVVCRQTEARKIRVWNREFALQSTSESVPGL
GPALAWKPSGSLIASTQDKPNQQDVVFFEKNGLLHGHFTLPFLKDEVKVNDLLWNADSSV
LAIWLEDLPKEDSSTLKSYVQLWTVGNYHWYLKQSLPFSTTGKNQIVSLLWDPVTPCRLH
VLCTGWRYLCCDWHWTTDRSSGNSANDLANVAVIDGNRVLVTVFRQTVVPPPMCTYRLLI
PHPVNQVIFSAHLGNDLAVLDASNQISVYKCGDKPNMDSTVKLGAVGGNGFKVPLTTPHL
EKRYSIQFGNNEEEEEEEVNALQLSFLTWVEDDTFLAISYSHSSSQSIIHHLTVTHSEVD
EEQGQLDVSSSVTVDGVVIGLCCCSKTKSLAVQLADGQVLKYLWESPSLAVEPWKNSEGI
PVRFVHPCTQMEVATIGGEECVLGLTDRCRFFINDTEVASNITSFAVCDDFLLVTTHSHT
CQVFSLSGASLKMLQAALSGSHEASGEILRKVERGSRIVTVVPQDTKLILQMPRGNLEVV
HHRALVLAQIRKWLDKLMFKEAFECMRKLRINLNLIHDHNPKVFLENVETFVKQIDSVNH
INLFFTELREEDVTKTMYPPPITKSVQVSTHPDGKKLDLICDAMRAAMEAINPRKFCLSI
LTSHVKKTTPELEIVLQKVQELQGNLPFDPESVSVEEALKYLLLLVDVNELFNHSLGTYD
FNLVLMVAEKSQKDPKEYLPFLNTLKKMETNYQRFTIDKYLKRYEKALGHLSKCG

IKI3

• PFAM accession number: PF04762
• Interpro abstract (IPR006849):

  Elongator complex protein 1 (also known as Iki3) is a component of the RNA polymerase II elongator complex, which is a major histone acetyltransferase component of the RNA polymerase II (RNAPII) holoenzyme. The eukaryotic elongator complex has been associated with many cellular activities, including transcriptional elongation [ (PUBMED:10024884) (PUBMED:11689709) ], but its main function is tRNA modification [ (PUBMED:15769872) (PUBMED:23165209) ]. It is required for the formation of 5-methoxy-carbonylmethyl (mcm5) and 5-carbamoylmethyl (ncm5) groups on uridine nucleosides present at the wobble position of many tRNAs [ (PUBMED:22889844) ].

• GO process: tRNA wobble uridine modification (GO:0002098)
• GO component: Elongator holoenzyme complex (GO:0033588)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry IKI3