The domain within your query sequence starts at position 7 and ends at position 83; the E-value for the IL33 domain shown below is 1.2e-31.
PLFFLLLGSQQKTKEFCHVYCMRLRSGLTIRKETSYFRKEPTKRYSLKSGTKHEENFSAY PRDSRKRSLLGSIQAFA
IL33 |
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| PFAM accession number: | PF15095 |
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| Interpro abstract (IPR026145): | This entry represents interleukin-33 (IL33), which that binds to and signals through IL1RL1/ST2 and its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8 [ (PUBMED:17185418) (PUBMED:22215666) ]. It also serves as a warning signal between cells at times of injury or cell death [ (PUBMED:22215666) ]. |
| GO function: | cytokine activity (GO:0005125) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry IL33