SMART: Pfam domain ImpE

ImpE

PFAM accession number:	PF07024
Interpro abstract (IPR009211):	This entry includes TagJ (also known as HsiE1), which is an accessory component of the bacterial type VI secretion system (T6SS). It plays a role in the interaction between ClpV and the TssC/TssB sheath [ (PUBMED:25305017) ]. The type VI secretion system (T6SS) is a supra-molecular bacterial complex that resembles phage tails. It is a toxin delivery systems which fires toxins into target cells upon contraction of its TssBC sheath [ (PUBMED:27288401) ]. Thirteen essential core proteins are conserved in all T6SSs: the membrane associated complex TssJ-TssL-TssM, the baseplate proteins TssE, TssF, TssG, and TssK, the bacteriophage-related puncturing complex composed of the tube (Hcp), the tip/puncturing device VgrG, and the contractile sheath structure (TssB and TssC). Finally, the starfish-shaped dodecameric protein, TssA, limits contractile sheath polymerization at its distal part when TagA captures TssA [ (PUBMED:31379775) ].

PFAM accession number:

PF07024

Interpro abstract (IPR009211):

This entry includes TagJ (also known as HsiE1), which is an accessory component of the bacterial type VI secretion system (T6SS). It plays a role in the interaction between ClpV and the TssC/TssB sheath [ (PUBMED:25305017) ].

The type VI secretion system (T6SS) is a supra-molecular bacterial complex that resembles phage tails. It is a toxin delivery systems which fires toxins into target cells upon contraction of its TssBC sheath [ (PUBMED:27288401) ]. Thirteen essential core proteins are conserved in all T6SSs: the membrane associated complex TssJ-TssL-TssM, the baseplate proteins TssE, TssF, TssG, and TssK, the bacteriophage-related puncturing complex composed of the tube (Hcp), the tip/puncturing device VgrG, and the contractile sheath structure (TssB and TssC). Finally, the starfish-shaped dodecameric protein, TssA, limits contractile sheath polymerization at its distal part when TagA captures TssA [ (PUBMED:31379775) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry ImpE