Ldh_2

• PFAM accession number: PF02615
• Interpro abstract (IPR003767):

  The malate dehydrogenase (MDH) of some extremophilies is more similar to the L-lactate dehydrogenases (L-LDH) EC 1.1.1.27 from various sources than to other MDHs [ (PUBMED:8476859) ].

  This family consists of bacterial and archaeal malate/L-lactate dehydrogenases and related proteins. The archaebacterial malate dehydrogenase EC 1.1.1.37 EC 1.1.1.82 deviates from the eubacterial and eukaryotic enzymes having a low selectivity for the coenzyme (NAD(H) or NADP(H)) and catalyzing the reduction of oxalacetate to malate more efficiently than the reverse reaction [ (PUBMED:2110059) ].

• GO process: oxidation-reduction process (GO:0055114)
• GO function: oxidoreductase activity (GO:0016491)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Ldh_2