SMART: Pfam domain Ldr

Ldr_toxin

PFAM accession number:	PF13940
Interpro abstract (IPR025253):	This family includes the Ldr (long direct repeat) toxins. In Escherichia coli there are four Ldr toxins, LdrA, LdrB, LdrC and LdrD. These toxins inhibit cell growth, decrease cell viability and cause nucleoid condensation. They are part of the type I toxin antitoxin (TA) system, where expression of the proteinaceous toxin is controlled by an antisense sRNA. For example, LdrD expression is inhibited by the antisense RNA RdlD, which functions as an antitoxin [ (PUBMED:12123448) ].

PFAM accession number:

PF13940

Interpro abstract (IPR025253):

This family includes the Ldr (long direct repeat) toxins. In Escherichia coli there are four Ldr toxins, LdrA, LdrB, LdrC and LdrD. These toxins inhibit cell growth, decrease cell viability and cause nucleoid condensation. They are part of the type I toxin antitoxin (TA) system, where expression of the proteinaceous toxin is controlled by an antisense sRNA. For example, LdrD expression is inhibited by the antisense RNA RdlD, which functions as an antitoxin [ (PUBMED:12123448) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Ldr_toxin