The domain within your query sequence starts at position 114 and ends at position 319; the E-value for the MCU domain shown below is 3.5e-78.
LQEEDRGIDRVAIYSPDGVRVAASTGIDLLLLDDFKLVINDLTYHVRPPKRDLLSHEDAA TLNDVKTLVQQLYTTLCIEQHQLNKERELVERLEDLKQQLAPLEKVRIEISRKAEKRTTL VLWGGLAYMATQFGILARLTWWEYSWDIMEPVTYFITYGSAMAMYAYFVMTRQEYVYPEA RDRQYLLFFHKGAKKSRFDLEKYNQL
MCU |
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PFAM accession number: | PF04678 |
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Interpro abstract (IPR006769): | This entry represents the C-terminal domain of MCU, which is a mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria [ (PUBMED:21685888) (PUBMED:21685886) (PUBMED:23101630) ]. This domain can also be found in MCUb, which negatively regulates the activity of MCU [ (PUBMED:23900286) ]. |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry MCU