SMART: Pfam domain META

META

PFAM accession number:	PF03724
Interpro abstract (IPR005184):	This entry represents a domain found in proteins of unknown function [ (PUBMED:12625841) ], some of which are described as heat shock protein (HslJ). In Helicobacter pylori (Campylobacter pylori) the protein is secreted e.g. ( O25998 ) and implicated in motility. In Leishmania spp. it is described as an essential protein, over-expression of which, in Leishmania amazonensis increases virulence ( O43987 [ (PUBMED:10403759) ]). In E. coli, hslJ is not induced by heat shock. It encodes a putative outer-membrane protein that is CysB-regulated and is involved in displaying novobiocin resistance [ (PUBMED:12892888) ]. A pair of cysteine residues show correlated conservation, suggesting that they form a disulphide bond.

PFAM accession number:

PF03724

Interpro abstract (IPR005184):

This entry represents a domain found in proteins of unknown function [ (PUBMED:12625841) ], some of which are described as heat shock protein (HslJ). In Helicobacter pylori (Campylobacter pylori) the protein is secreted e.g. ( O25998 ) and implicated in motility. In Leishmania spp. it is described as an essential protein, over-expression of which, in Leishmania amazonensis increases virulence ( O43987 [ (PUBMED:10403759) ]). In E. coli, hslJ is not induced by heat shock. It encodes a putative outer-membrane protein that is CysB-regulated and is involved in displaying novobiocin resistance [ (PUBMED:12892888) ].

A pair of cysteine residues show correlated conservation, suggesting that they form a disulphide bond.

This is a PFAM domain. For full annotation and more information, please see the PFAM entry META