The domain within your query sequence starts at position 283 and ends at position 765; the E-value for the Med12-LCEWAV domain shown below is 5e-187.

EFVQSAYLSRRLAYFCARRLSLLLSDSPNLLAAHSPHMIIGTNNTSIGTPSPGTPGPGMS
PVQLAFSDFLSCAQHGPLVYGLSCMLQTVTLCCPSALVWNYSTNENKISNPGSPLDLLQV
APSSLPMPGGNTAFNQQVRARIYEVEQQIKQRGRAVEVRWSFDKCQESTAGVTISRVLHT
LEVLDRHCFDRTDSSNSMETLYHKIFWANQNKDNQEVAPNDEAVVTLLCEWAVSCKRSGK
HRAMAVAKLLEKRQAEIEAERCGESEVLDEKESISSASLAGSSLPVFQNVLLRFLDTQAP
ALSDPNSECEKVEFVNLVLLFCEFIRHDVFSHDAYMCTLISRGDLSVTASTGLRSPAGEN
SDEHYSKDHDMKMEEHSVMARLGLGSGATHIFDDVDKSDFKSDPASEFPIFSPMPGESCE
NINPSLSRRLSVNGEKLLKREKPRELIFPSNYDLLRHLQYATHFPIPLDESSSHECNQRT
ILL

Med12-LCEWAV

Med12-LCEWAV
PFAM accession number:PF12145
Interpro abstract (IPR021990):

This domain is found in eukaryotes, and is typically between 325 and 354 amino acids in length. The function of this particular region of the Mediator subunit Med12 is not known, but there is a conserved sequence motif: LCEWAV, from which the name derives.

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Med12-LCEWAV