SMART: Pfam domain MgtC

MgtC

PFAM accession number:	PF02308
Interpro abstract (IPR003416):	This entry includes a group of transmembrane proteins, including MgtC, SapB, SrpB and YhiD from bacteria. The MgtC protein is found in an operon with the Mg2+ transporter protein MgtB. However, MgtC is not a Mg2+ transporter [ (PUBMED:9673265) (PUBMED:16855249) ]. The expression of MgtC is a virulence factor required for growth in low Mg2+ medium and for intramacrophage survival [ (PUBMED:17176255) ]. MgtC may be involved in regulating membrane potential by activating Na+/K+-ATPase [ (PUBMED:9673265) (PUBMED:16855249) ]. YhiD from E. coli is an integral membrane protein related to MgtC. It has been suggested to be an essential component for the Mg2+ uptake system in E. coli [ (PUBMED:19798051) ].
GO component:	membrane (GO:0016020)

PFAM accession number:

PF02308

Interpro abstract (IPR003416):

This entry includes a group of transmembrane proteins, including MgtC, SapB, SrpB and YhiD from bacteria.

The MgtC protein is found in an operon with the Mg2+ transporter protein MgtB. However, MgtC is not a Mg2+ transporter [ (PUBMED:9673265) (PUBMED:16855249) ]. The expression of MgtC is a virulence factor required for growth in low Mg2+ medium and for intramacrophage survival [ (PUBMED:17176255) ]. MgtC may be involved in regulating membrane potential by activating Na+/K+-ATPase [ (PUBMED:9673265) (PUBMED:16855249) ].

YhiD from E. coli is an integral membrane protein related to MgtC. It has been suggested to be an essential component for the Mg2+ uptake system in E. coli [ (PUBMED:19798051) ].

GO component:

membrane (GO:0016020)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry MgtC