Microvir_lysis

• PFAM accession number: PF04517
• Interpro abstract (IPR007605):

  E protein causes host cell lysis by inhibiting MraY, a peptidoglycan biosynthesis enzyme. This leads to cell wall failure at septation [ (PUBMED:12100551) ]. The N-terminal transmembrane region matches the signal peptide model and must be omitted from the family.

• GO process: modulation by virus of host cellular process (GO:0019054)
• GO function: enzyme inhibitor activity (GO:0004857)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Microvir_lysis