SMART: Pfam domain MotB

MotB_plug

PFAM accession number:	PF13677
Interpro abstract (IPR025713):	This domain is found in MotB, a component of the Escherichia coli MotA/MotB proton-channel complex that forms the stator of the bacterial membrane flagellar motor. Key residues in MotB act as a plug to prevent premature proton flow. The plug is in the periplasm just C-terminal to the MotB TM (transmembrane helix), consisting of an amphipathic alpha helix flanked by Pro-52 and Pro-65, eg in D3V2T1 . In addition to the Pro residues, Ile-58, Tyr-61, and Phe 62 are also essential for plug function [ (PUBMED:17052729) (PUBMED:14705929) ].

PFAM accession number:

PF13677

Interpro abstract (IPR025713):

This domain is found in MotB, a component of the Escherichia coli MotA/MotB proton-channel complex that forms the stator of the bacterial membrane flagellar motor. Key residues in MotB act as a plug to prevent premature proton flow. The plug is in the periplasm just C-terminal to the MotB TM (transmembrane helix), consisting of an amphipathic alpha helix flanked by Pro-52 and Pro-65, eg in D3V2T1 . In addition to the Pro residues, Ile-58, Tyr-61, and Phe 62 are also essential for plug function [ (PUBMED:17052729) (PUBMED:14705929) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry MotB_plug