Mqo

• PFAM accession number: PF06039
• Interpro abstract (IPR006231):

  The membrane-associated enzyme, malate:quinone-oxidoreductase, is an alternative to the better-known NAD-dependent malate dehydrogenase as part of the TCA cycle. The reduction of a quinone rather than NAD+ makes the reaction essentially irreversible in the direction of malate oxidation to oxaloacetate. Both forms of malate dehydrogenase are active in Escherichia coli; disruption of this form causes less phenotypic change. In some bacteria, this form is the only or the more important malate dehydrogenase [ (PUBMED:11092847) ].

• GO process: tricarboxylic acid cycle (GO:0006099)
• GO function: malate dehydrogenase (quinone) activity (GO:0008924)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Mqo