The domain within your query sequence starts at position 6 and ends at position 178; the E-value for the NTPase_1 domain shown below is 3.2e-63.



PFAM accession number:PF03266
Interpro abstract (IPR004948):

This entry represents a family of nucleoside-triphosphatases which have activity towards ATP, GTP, CTP, TTP and UTP and may hydrolyse nucleoside diphosphates with lower efficiency [ (PUBMED:17291528) ]. It includes proteins from bacteria to human, and the function was determined first in a hyperthermophilic bacterium to be an NTPase [ (PUBMED:14503925) ]. The structure of one member-sequence represents a variation of the RecA fold, and implies that the function might be that of a DNA/RNA modifying enzyme [ (PUBMED:15777481) ]. The sequence carries both a Walker A and Walker B motif which together are characteristic of ATPases or GTPases. The protein exhibits an increased expression profile in human liver cholangiocarcinoma when compared to normal tissue [ (PUBMED:17291528) ].

GO function:nucleoside-triphosphatase activity (GO:0017111)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry NTPase_1