The domain within your query sequence starts at position 66 and ends at position 227; the E-value for the Neuromodulin domain shown below is 1.9e-62.



PFAM accession number:PF06614
Interpro abstract (IPR017454):

This entry represents the C-teminal domain of neuromodulin, which is a component of the motile growth cones. It is a membrane protein whose expression is widely correlated with successful axon elongation and is a crucial component of an effective regeneration response in the nervous system [ (PUBMED:3272162) (PUBMED:2641999) ]. Although its function is uncertain, the N-terminal region is well conserved and contains both a calmodulin binding domain, and sites for acylation, membrane attachment and protein kinase C phosphorylation. Structural predictions suggest that this C-terminal domain may exist as an extended, negatively-charged rod with some similarity to the side arms of neurofilaments, indicating that the biological role of neuromodulin may depend on its ability to form a dynamic membrane-cytoplasm-calmodulin complex [ (PUBMED:2641999) ].

GO process:regulation of growth (GO:0040008)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Neuromodulin