The domain within your query sequence starts at position 443 and ends at position 545; the E-value for the Occludin_ELL domain shown below is 6.6e-33.



PFAM accession number:PF07303
Interpro abstract (IPR010844):

This represents a conserved region approximately 100 residues long within eukaryotic occludin proteins and the RNA polymerase II elongation factor ELL. Occludin is an integral membrane protein that localises to tight junctions [(PUBMED:8276896)], while ELL is an elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by polymerase at multiple sites along the DNA [(PUBMED:8596958)]. This shared domain is thought to mediate protein interactions [(PUBMED:8276896)].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Occludin_ELL