The domain within your query sequence starts at position 40 and ends at position 213; the E-value for the PRF domain shown below is 6.5e-11.



PFAM accession number:PF06875
Interpro abstract (IPR010681):

This family includes plethodontid receptivity factor (PRF) proteins which seem to be specific to Plethodon jordani (Jordan's salamander). PRF is a courtship pheromone produced by males increase female receptivity [(PUBMED:10489368)].

This family also includes cardiotrophin-2 (neuropoietin) and cardiotrophin-like cytokine factor 1 (CLCF1) from mammals, which share sequence similarity to PRF [(PUBMED:15014164)]. They are four-helix bundle cytokines that signal through the gp130 receptor subunit [(PUBMED:26198769)].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry PRF