The domain within your query sequence starts at position 1 and ends at position 504; the E-value for the Proteasom_PSMB domain shown below is 3.8e-199.

MAAQAVSLLREVARLEAPLEELRALQSVVQAVPLHELREQAAELRLRPLFSLLNQNNREQ
TALCVSILERLLQAVEPIHLARNLRLDLQRGLTHPDDSVKTLTLSQIGRIVENSEAVTEI
LNNAELLKQIVYCIGGENLSVAKAAIKSLSRISLTQAGLEALFESNLLDDLKNVMKTNDV
VRYRVYELIIDISSVSSESLNYCTTSGLVTQLLKELTGEDVLVRATCIEMVTSLAYTHHG
RQYLAQEGVIDQISNIIVGADSDPFSGFYLPGFVKFFGNLAVMDSPQQICERYPVFLEKV
FEMADSQDPTMIGVAVDTVGILGSSVEGKQVLQKTGTRFERVLMRVGYQAKNASTELKIR
CLDAVSSLLYLSPEQQTDDFLGMTESWFSSMSRDSLELFRGISNQPFPELHCAALKVFTA
IADQPWAQRLMFNSPGFVEFVMDRSVEHDKASKDAKYELVKALANSKTVAEIFGNSNYLR
LRAYLSEGPYYVKPVATTAVEGAD

Proteasom_PSMB

Proteasom_PSMB
PFAM accession number:PF10508
Interpro abstract (IPR019538):

The 26S proteasome is an enzymatic complex that degrades ubiquitinated proteins in eukaryotic cells. 26S proteasome non-ATPase regulatory subunit 5 (PSMD5) is one of a number of chaperones that are involved in the assembly of the proteasome. The chaperones dissociate before 26S proteasome formation is complete [ (PUBMED:19490896) ].

TNF-alpha/NFkB inhibits 26S proteasome assembly via abnormal expression of PSMD5, establishing a link between inflammation and chronic neurodegenerative diseases with altered ubiquitin-proteasome system function [ (PUBMED:22921402) ].

GO process:proteasome assembly (GO:0043248)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Proteasom_PSMB