Rhodanese

• PFAM accession number: PF00581
• Interpro abstract (IPR001763):

  Rhodanese, a sulphurtransferase involved in cyanide detoxification (see IPR001307 ) shares evolutionary relationship with a large family of proteins [ (PUBMED:9733650) ], including

  • Cdc25 phosphatase catalytic domain.
  • non-catalytic domains of eukaryotic dual-specificity MAPK-phosphatases.
  • non-catalytic domains of yeast PTP-type MAPK-phosphatases.
  • non-catalytic domains of yeast Ubp4, Ubp5, Ubp7.
  • non-catalytic domains of mammalian Ubp-Y.
  • Drosophila heat shock protein HSP-67BB.
  • several bacterial cold-shock and phage shock proteins.
  • plant senescence associated proteins.
  • catalytic and non-catalytic domains of rhodanese (see IPR001307 ).

  Rhodanese has an internal duplication. This domain is found as a single copy in other proteins, including phosphatases and ubiquitin C-terminal hydrolases [ (PUBMED:8702871) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Rhodanese