The domain within your query sequence starts at position 11 and ends at position 248; the E-value for the SAICAR_synt domain shown below is 4e-56.



PFAM accession number:PF01259
Interpro abstract (IPR028923):

Phosphoribosylaminoimidazole-succinocarboxamide synthase ( EC ) (SAICAR synthetase) catalyses the seventh step in the de novo purine biosynthetic pathway; the ATP-dependent conversion of 5'-phosphoribosyl-5-aminoimidazole-4-carboxylic acid and aspartic acid to SAICAR [ (PUBMED:1574589) ].

This domain can be found in SAICAR synthetases as a monofunctional protein from the bacteria (purC), fungi (ADE1) and plants (Pur7). In animals, this domain can be found in the N-terminal domain of a multifunctional enzyme (ADE2) possessing both the SAICAR synthetase and the phosphoribosylaminoimidazole carboxylase (AIR carboxylase) activity.

This is a PFAM domain. For full annotation and more information, please see the PFAM entry SAICAR_synt