SecM

• PFAM accession number: PF06558
• Interpro abstract (IPR009502):

  This family consists of several bacterial Secretion monitor precursor (SecM) proteins. SecM is known to regulate SecA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation. The eubacterial protein secretion machinery consists of a number of soluble and membrane associated components. One critical element is SecA ATPase, which acts as a molecular motor to promote protein secretion at translocation sites that consist of SecYE, the SecA receptor, and SecG and SecDFyajC proteins, which regulate SecA membrane cycling [ (PUBMED:10986266) ].

• GO function: translation regulator activity (GO:0045182)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry SecM