SMART: Pfam domain Spc7

Spc7

PFAM accession number:	PF08317
Interpro abstract (IPR013253):	This domain is found in cell division proteins which are required for kinetochore-spindle association [ (PUBMED:15371542) ]. Proteins containing this domain include budding yeast Spc105 and fission yeast Spc7. Spc7 is a component of the NMS (Ndc80-MIND-Spc7) super complex, which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle [ (PUBMED:22711988) ]. Spc105 and Kre28 forms a kinetochore complex, which is required for kinetochore binding by a discrete subset of kMAPs (BIM1, BIK1 and SLK19) and motors (CIN8, KAR3) [ (PUBMED:19893618) ].

PFAM accession number:

PF08317

Interpro abstract (IPR013253):

This domain is found in cell division proteins which are required for kinetochore-spindle association [ (PUBMED:15371542) ]. Proteins containing this domain include budding yeast Spc105 and fission yeast Spc7.

Spc7 is a component of the NMS (Ndc80-MIND-Spc7) super complex, which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle [ (PUBMED:22711988) ]. Spc105 and Kre28 forms a kinetochore complex, which is required for kinetochore binding by a discrete subset of kMAPs (BIM1, BIK1 and SLK19) and motors (CIN8, KAR3) [ (PUBMED:19893618) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Spc7