The domain within your query sequence starts at position 5 and ends at position 72; the E-value for the Sperm_Ag_HE2 domain shown below is 3.7e-35.
LLPFFASLLFAALLFPGLSNASSINHLVTEPPSFPKDEFPARGVNGSQLLHHRVKRLPPR TPPYHEPE
Sperm_Ag_HE2 |
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PFAM accession number: | PF05324 |
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Interpro abstract (IPR007988): | This family consists of several variants of the human and chimpanzee (Pan troglodytes) sperm antigen proteins (HE2 and EP2 respectively). The EP2 gene codes for a family of androgen-dependent, epididymis-specific secretory proteins, known as sperm-associated antigen 11.The EP2 gene uses alternative promoters and differential splicing to produce a family of variant messages. The translated putative protein variants differ significantly from each other. Some of these putative proteins have similarity to beta-defensins, a family of antimicrobial peptides [ (PUBMED:10819450) ]. |
GO component: | extracellular region (GO:0005576) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry Sperm_Ag_HE2