The domain within your query sequence starts at position 25 and ends at position 114; the E-value for the Spexin domain shown below is 4.3e-55.
SGAPQRLSEKRNWTPQAMLYLKGAQGRRFLSDQSRRKELADRPPPERRNPDLELLTLPEA AALFLASLEKSQKGADEGGNFDKSELLEDR
Spexin |
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PFAM accession number: | PF15171 |
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Interpro abstract (IPR028126): | Spexin, alternatively named NPQ, is a peptide hormone and is derived from a pro-hormone. This family of proteins has a role in inducing stomach wall contraction and is expressed in the submucosal layer of the mouse oesophagus and stomach. Spexin, like most peptide hormones, is a ligand for G-protein coupled receptors [ (PUBMED:17284679) ]. Spexin is also thought to have a role in controlling arterial blood pressure as well as salt and water balance [ (PUBMED:22038051) ]. |
GO function: | neuropeptide hormone activity (GO:0005184) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry Spexin