The domain within your query sequence starts at position 98 and ends at position 227; the E-value for the Spy1 domain shown below is 4.9e-65.
EHHKVFTKLLEDPVVKKFLTWDKMLRVSDKYLLSMVIAYFSRAGLFSWQYRPIHFFLALY LANDMEEDNQAPKQDIFYFLYGKSYAQRPMFHKLRFQFIRSMGWKIWVSREECEEIQAYN PDLWVWARDR
Spy1 |
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PFAM accession number: | PF11357 |
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Interpro abstract (IPR020984): | Speedy (Spy1) is a cell cycle regulatory protein which activates CDK2, the major kinase that allows progression through G1/S phase and further replication events. Spy1 expression overcomes a p27-induced cell cycle arrest to allow for DNA synthesis, so cell cycle progression occurs due to an interaction between Spy1 and p27 [ (PUBMED:17671428) ]. Spy1 is also known as Ringo protein A. |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry Spy1