The domain within your query sequence starts at position 6 and ends at position 322; the E-value for the TAS2R domain shown below is 3.1e-82.

ISTSDIFTFTIILFVELVIGILGNGFIALVNIMDWTKRRSISSADQILTALAITRFLYVW
FMIICILLFMLCPHLLTRSEIVTSIGIIWIVNNHFSVWLATCLGVFYFLKIANFSNSLFL
YLKWRVKKVVLMIIQVSMIFLILNLLSLSMYDQFSIDVYEGNTSYNLGDSTPFPTISLFI
NSSKVFVITNSSHIFLPINSLFMLIPFTVSLVAFLMLIFSLWKHHKKMQVNAKPPRDAST
MAHIKALQTGFSFLLLYAVYLLFIVIGMLSLRLIGGKLILLFDHISGIGFPISHSFVLIL
GNNKLRQASLSVLHCLR

TAS2R

TAS2R
PFAM accession number:PF05296
Interpro abstract (IPR007960):

This family consists of several forms of mammalian taste receptor proteins (TAS2Rs). TAS2Rs are G protein-coupled receptors expressed in subsets of taste receptor cells of the tongue and palate epithelia and are organised in the genome in clusters. The proteins are genetically linked to loci that influence bitter perception in mice and humans [ (PUBMED:10761934) ]. These receptors may play a role in sensing the chemical composition of the gastrointestinal content.

GO process:sensory perception of taste (GO:0050909), G protein-coupled receptor signaling pathway (GO:0007186)
GO component:integral component of membrane (GO:0016021)
GO function:G protein-coupled receptor activity (GO:0004930)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry TAS2R