The domain within your query sequence starts at position 10 and ends at position 85; the E-value for the TC1 domain shown below is 5.2e-40.
TSMSSSLRVSPSIHGYHFDTAARKKAVGNIFENIDQESLQRLFRNSGDKKAEERAKIIFA IDQDLEEKTRALMALK
TC1 |
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PFAM accession number: | PF15063 |
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Interpro abstract (IPR020282): | This entry includes arginine vasopressin-induced protein 1 (Avpi1) and C8orf4 protein. Avpi1 is thought to be involved in MAP kinase activation, epithelial sodium channel (ENaC) down-regulation and cell cycling [ (PUBMED:12356727) ]. C8orf4, also known as transcriptional and immune response regulator (TCIM) or thyroid cancer 1 (TC-1), plays important roles in many signalling pathways, such as Wnt/beta-catenin signalling pathway, and is involved in the development of many cancers [ (PUBMED:25869879) ]. C8orf4 also suppresses NOTCH2 signalling in liver cancer stem cells [ (PUBMED:25985737) ]. |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry TC1