The domain within your query sequence starts at position 147 and ends at position 277; the E-value for the TMEM169 domain shown below is 6.1e-66.

RRACQVGADQGPHVVLWTLVCLPVVFVLSFVVSFYYGTITWYNIFLVYNEERTFWHKISC
CPCLILFYPVLIMTMASSLGLYAAVAQLSWSWAAWWRAACDMEKGFCGWLCSKLGLEDCS
PYSIVELLESD

TMEM169

 TMEM169
PFAM accession number:PF15052
Interpro abstract (IPR029386):

This entry represents a group of eukaryotic proteins that are approximately 130 amino acids in length. They contain structured transmembrane helices.

This is a PFAM domain. For full annotation and more information, please see the PFAM entry TMEM169