The domain within your query sequence starts at position 1 and ends at position 138; the E-value for the TP_methylase domain shown below is 3.7e-22.
MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLILADREE VEQEADNIFKDADVSDVAFLVVGDPFGATTHSDLILRATKLGIPYQVIHNASIMNAVGCC GLQVMPQRKCVLFPGSYK
TP_methylase |
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PFAM accession number: | PF00590 |
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Interpro abstract (IPR000878): | Tetrapyrroles are large macrocyclic compounds derived from a common biosynthetic pathway [(PUBMED:11215515)]. The end-product, uroporphyrinogen III, is used to synthesise a number of important molecules, including cobalamin (vitamin B12), haem, sirohaem, chlorophyll, coenzyme F430 and phytochromobilin [(PUBMED:17227226)]. These enzymes catalyse the methylation of their substrates using S-adenosyl-L-methionine as a methyl source. Enzymes in this family include:
This entry represents a tetrapyrrole methylase domain, which consist of two non-similar subdomains [(PUBMED:15522295)]. |
GO process: | metabolic process (GO:0008152) |
GO function: | methyltransferase activity (GO:0008168) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry TP_methylase