TerC

• PFAM accession number: PF03741
• Interpro abstract (IPR005496):

  A family containing a number of integral membrane proteins is named after TerC protein. TerC has been implicated in resistance to tellurium, and may be involved in efflux of tellurium ions. The tellurite-resistant Escherichia coli strain KL53 was found during testing of a group of clinical isolates for antibiotic and heavy metal ion resistance [ (PUBMED:10069007) ]. The determinant of the strain's tellurite resistance was located on a large conjugative plasmid, and analyses showed the genes terB, terC, terD and terE were essential for conservation of this resistance. Members of this family contain a number of conserved aspartates which may be involved in metal ion binding.

  A TerC homologue is known from the chloroplast thylakoid membrane from Arabidopsis which is important for thylakoid membrane biogenesis in the developing chloroplast [ (PUBMED:18429937) ]; it is required for insertion of proteins into the thylakoid membrane [ (PUBMED:24612058) ].

• GO component: integral component of membrane (GO:0016021)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry TerC