TerD

• PFAM accession number: PF02342
• Interpro abstract (IPR003325):

  The TerD domain is found in TerD family proteins that include the paralogous TerD, TerA, TerE, TerF and TerZ proteins [ (PUBMED:10203839) (PUBMED:23044854) ]. It is found in a stress response operon with TerB and TerC. TerD has a maximum of two calcium binding sites [ (PUBMED:23044854) (PUBMED:21112337) ] depending on the conservation of aspartates [ (PUBMED:23044854) ]. It has various fusions to nuclease domains, RNA binding domains, ubiquitin related domains, and metal binding domains. The ter gene products lie at the centre of membrane-linked metal recognition complexes with regulatory ramifications encompassing phosphorylation-dependent signal transduction, RNA-dependent regulation, biosynthesis of nucleoside-like metabolites and DNA processing linked to novel pathways [ (PUBMED:23044854) ].

  TerD domain is also found in cAMP binding protein, chemical-damaging agent resistance proteins and general stress proteins. The cellular Slime mould, Dictyostelium discoideum, contains a cAMP-binding protein, CABP1, which is composed of two subunits. The C-terminal half of these subunits contain this domain [ (PUBMED:2176639) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry TerD