Terpene_synth_C

 Terpene_synth_C
PFAM accession number:PF03936
Interpro abstract (IPR005630):

Sequences containing this domain belong to the terpene synthase family. It has been suggested that this gene family be designated tps (for terpene synthase). Sequence comparisons reveal similarities between the monoterpene (C 10 ) synthases, sesquiterpene (C 15 ) synthases and the diterpene (C 20 ) synthases. It has been split into six subgroups on the basis of phylogeny, called Tpsa-Tpsf [ (PUBMED:9268308) ].

  • Tpsa includes vetispiradiene synthase Q39979 5-epi- aristolochene synthase, Q40577 and (+)-delta-cadinene synthase P93665 .
  • Tpsb includes (-)-limonene synthase, Q40322 .
  • Tpsc includes copalyl diphosphate synthase (kaurene synthase A), O04408 .
  • Tpsd includes taxadiene synthase, Q41594 pinene synthase, O24475 and myrcene synthase, O24474 .
  • Tpse includes ent-kaurene synthase B Q39548 .
  • Tpsf includes linalool synthase Q9ZPN5 .

In the fungus Phaeosphaeria sp. (strain L487) the synthesis of ent-kaurene from geranylgeranyl dophosphate is promoted by a single bifunctional protein [ (PUBMED:9268298) ].

This domain is involved in the cyclization of linear terpenes [ (PUBMED:9295272) (PUBMED:12432096) (PUBMED:17261032) (PUBMED:20131801) (PUBMED:20624401) ].

GO function:magnesium ion binding (GO:0000287), lyase activity (GO:0016829), terpene synthase activity (GO:0010333)

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Terpene_synth_C