The domain within your query sequence starts at position 339 and ends at position 392; the E-value for the VEGF_C domain shown below is 1.9e-31.
SWSVHCEPCSERRKHLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
VEGF_C |
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PFAM accession number: | PF14554 |
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Interpro abstract (IPR027928): | This short domain is found at the C terminus of vascular endothelial growth factor (VEGF). It has been shown to have heparin binding activity [ (PUBMED:12061718) ]. Proteins containing this domain include VEGF-A, which is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth [ (PUBMED:7556923) ]. VEGF-A also promotes a wide range of neuronal functions, including neurogenesis, neuronal migration, neuronal survival and axon guidance [ (PUBMED:22434866) ]. |
GO function: | heparin binding (GO:0008201) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry VEGF_C