SMART: Pfam domain Virul_fac

Virul_fac_BrkB

PFAM accession number:	PF03631
Interpro abstract (IPR017039):	Members of this family include the largely uncharacterised BrkB (Bordetella resist killing by serum B) from Bordetella pertussis. It is essential for resistance to complement-dependent killing by serum in Bordetella pertussis [ (PUBMED:7927748) ]. Some members have an additional C-terminal domain. Paralogs from E. coli (yhjD) and Mycobactrium tuberculosis (Rv3335c) are part of a smaller, related subfamily that form their own cluster [ (PUBMED:1400219) ]. This family was originally predicted to be ribonuclease BN [ (PUBMED:15764599) ] but this prediction has since been shown to be incorrect [ (PUBMED:8955422) ].

PFAM accession number:

PF03631

Interpro abstract (IPR017039):

Members of this family include the largely uncharacterised BrkB (Bordetella resist killing by serum B) from Bordetella pertussis. It is essential for resistance to complement-dependent killing by serum in Bordetella pertussis [ (PUBMED:7927748) ]. Some members have an additional C-terminal domain. Paralogs from E. coli (yhjD) and Mycobactrium tuberculosis (Rv3335c) are part of a smaller, related subfamily that form their own cluster [ (PUBMED:1400219) ].

This family was originally predicted to be ribonuclease BN [ (PUBMED:15764599) ] but this prediction has since been shown to be incorrect [ (PUBMED:8955422) ].

This is a PFAM domain. For full annotation and more information, please see the PFAM entry Virul_fac_BrkB