The domain within your query sequence starts at position 71 and ends at position 101; the E-value for the WSK domain shown below is 3.3e-13.
RQPAGAWASIKGLVTHRKRSEPAKKQKPPEA
WSK |
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PFAM accession number: | PF03832 |
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Interpro abstract (IPR001573): | The AKAP CaM-binding motif (also known as the WSK motif) is short motif, named after three conserved residues found in the WXSXK motif, found in protein kinase A anchoring proteins. The A kinase-anchoring proteins AKAP-5 and AKAP-12 (Gravin) bind calmodulin (CaM), a Ca(2+)-sensing protein that is expressed in all eukaryotic cells and mediates many essential processes driven by Ca(2+), including long-term changes in synaptic connections in the brain, apoptosis, and immune responses. The AKAP CaM-binding motif contains hydrophobic amino acids in a 1-4-7-8 pattern within an helix [ (PUBMED:29162807) ]. |
GO function: | calmodulin binding (GO:0005516) |
This is a PFAM domain. For full annotation and more information, please see the PFAM entry WSK