The domain within your query sequence starts at position 1151 and ends at position 1279; the E-value for the RPT_1 domain shown below is 3.97e-6.

SPTQDRPESSTVLKVTPRVLLKERSGAGSPPGKRDQKSLLPNSSQDELMEVEKSEQPLSQ
VLPSLSPEHKEMPGSNIESSPEVEERPAVLSALDQSQSQPSKAAETPAVASCWSGPQVSP
EHKELSHSP

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.