The domain within your query sequence starts at position 1277 and ends at position 1489; the E-value for the RPT_1 domain shown below is 6.8e-5.

LTPENPSSQQTGFSSFKASLRLPSCVSLPSADSGITQHPLSTESDSKVKSSHLQIPELQH
RLSKISQLIPPQQDSLKALQEQLATQREAIIHSRQEAHEETLREWKEKIFPEQVGPFSPL
IPQHSLASFPVSDTERAQELCSTNSDTISSGYPEMLELPDRTLGLSHTALPQQNNLTAHP
EHLHAQTNFFHSTEKAQEGLVFPRPCQFEEMSA

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.