The domain within your query sequence starts at position 133 and ends at position 218; the E-value for the RPT_1 domain shown below is 3.4e-10.

PRPSLVALPGPVVAPGANVSLRCAGRIPGMSFALYRVGVATPLQYIDSVQPWADFLLIGT
HTPGTYCCYYHTPSAPYVLSQRSQPL

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.