The domain within your query sequence starts at position 1540 and ends at position 1728; the E-value for the RPT_1 domain shown below is 9.97e-23.

AISTSASFGGTLNNSASFGGAINTSASFGGVLNNSAGFGGAINTSANFGGALTNSAGFGG
AISTSASFGGALNNSAGFGGAISTSASFGGALNNSAGFGGAISTNASFGGAISNSPDFGG
AFSTSVGFGGTLNTTDFGSTHSNSISFGSAPTTSVSFGGSHSTNLCFGGAPSTSLCFGSA
SNTNLCFGG

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.