The domain within your query sequence starts at position 155 and ends at position 240; the E-value for the RPT_1 domain shown below is 3.73e-10.

TAPGNMQPPVRLQPLLSSRQTRNGSKITSGSKPKGSLLESEALFPLGGKKAMMKFRNYMD
HSQKEDLYQLPHINSYHTPVPPTPQP

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.