The domain within your query sequence starts at position 155 and ends at position 350; the E-value for the RPT_1 domain shown below is 1.59e-7.

KFDSEPSAAALEHPVRAFGLSEASETALVLEPPVVSMEVQESHVLETLKPATKAAELSVV
STSVISEQSEQPMPGMLEPSMTKILDSFTAAPVPMSTAALKSPEPVVTMSVEYQKSVLKS
LETMPPETSKTTLVELPIAKVVEPSETLTIVSETPTEVHPEPSPSTMDFPESSTTDVQRL
PEQPVEAPSEIADSSM

This is a significant internal repeat in the query protein sequence, as detected by the Prospero program.